|
|
enzyme_N6-(dihydrolipoyl)lysine + NAD+ <=> [dihydrolipoyllysine-residue(2-methylpropanoyl)transferase]-lipoyllysine + NADH + H+
|
1.8.1.4
dihydrolipoyl dehydrogenase
|
–
|
MK
|
| |
BRENDA:
BR36970
KEGG:
R03815;
R07618;
R08550
MetaCyc:
1.8.1.4-RXN;
RXN-7716
SABIO-RK:
9140
|
|
|
|
acetyl-CoA + enzyme_N6-(dihydrolipoyl)lysine <=> CoA + enzyme_N6-(S-acetyldihydrolipoyl)lysine
|
2.3.1.12
dihydrolipoyllysine-residue acetyltransferase
|
–
|
BK
|
| |
BRENDA:
BR43982
KEGG:
R02569
|
|
|
|
succinyl-CoA + enzyme_N6-(dihydrolipoyl)lysine <=> CoA + enzyme_N6-(S-succinyldihydrolipoyl)lysine
|
2.3.1.61
dihydrolipoyllysine-residue succinyltransferase
|
–
|
BK
|
| |
BRENDA:
BR44062
KEGG:
R02570
|
|
|
|
isobutyryl-CoA + enzyme_N6-(dihydrolipoyl)lysine <=> CoA + enzyme_N6-(S-[2-methylpropanoyl]dihydrolipoyl)lysine
|
2.3.1.168
dihydrolipoyllysine-residue (2-methylpropanoyl)transferase
|
–
|
K
|
| |
BRENDA:
BR48046
KEGG:
R02662
|
|
|
|
enzyme_N6-(dihydrolipoyl)lysine + ROOH <=> [dihydrolipoyllysine-residue(2-methylpropanoyl)transferase]-lipoyllysine + H2O + an_alcohol
|
1.11.1.28
lipoyl-dependent peroxiredoxin
|
–
|
|
| |
KEGG:
R12602
MetaCyc:
RXN-20690
|
|
|
|
glutaryl-CoA + enzyme_N6-(dihydrolipoyl)lysine <=> CoA + [Dihydrolipoyllysine-residue_succinyltransferase]_S-glutaryldihydrolipoyllysine
|
2.3.1.61
dihydrolipoyllysine-residue succinyltransferase
|
–
|
|
| |
KEGG:
R02571
|
|
|
|
(S)-2-methylbutanoyl-CoA + enzyme_N6-(dihydrolipoyl)lysine <=> CoA + [dihydrolipoyllysine-residue_(2-methylpropanoyl)transferase]_S-(2-methylbutanoyl)dihydrolipoyllysine
|
2.3.1.168
dihydrolipoyllysine-residue (2-methylpropanoyl)transferase
|
–
|
K
|
| |
KEGG:
R03174
|
|
|
|
isovaleryl-CoA + enzyme_N6-(dihydrolipoyl)lysine <=> CoA + [dihydrolipoyllysine-residue_(2-methylpropanoyl)transferase]_S-(3-methylbutanoyl)dihydrolipoyllysine
|
2.3.1.168
dihydrolipoyllysine-residue (2-methylpropanoyl)transferase
|
–
|
K
|
| |
KEGG:
R04097
|
|
|
|
protein_N6-(octanoyl)lysine + an_[Fe-S]_cluster_scaffold_protein_carrying_a_[4Fe-4S]2+_cluster + 2 S-adenosyl-L-methionine + 2 [2Fe-2S]-center + 8 H+ <=> enzyme_N6-(dihydrolipoyl)lysine + an_[Fe-S]_cluster_scaffold_protein + 2 Sulfide + 4 Fe2+ + 2 L-methionine + 2 5''-Deoxyadenosine + 2 [2Fe-2S]-center
|
2.8.1.8
lipoyl synthase
|
–
|
|
| |
KEGG:
R07767
|
|
|
|
propionyl-CoA + enzyme_N6-(dihydrolipoyl)lysine <=> CoA + Enzyme_N6-(S-propyldihydrolipoyl)lysine
|
2.3.1.168
dihydrolipoyllysine-residue (2-methylpropanoyl)transferase
|
–
|
K
|
| |
KEGG:
R10998
|
|
|
|
[Lipoyl-carrier_protein_E2]-N6-octanoyl-L-lysine + an_[Fe-S]_cluster_scaffold_protein_carrying_a_[4Fe-4S]2+_cluster + 2 S-adenosyl-L-methionine + 2 [2Fe-2S]-center + 8 H+ <=> enzyme_N6-(dihydrolipoyl)lysine + an_[Fe-S]_cluster_scaffold_protein + 2 Sulfide + 4 Fe2+ + 2 L-methionine + 2 5''-Deoxyadenosine + 2 [2Fe-2S]-center
|
2.8.1.8
lipoyl synthase
|
–
|
K
|
| |
KEGG:
R12423
|
|
|
|
dihydrolipoylprotein + Lipoyl-carrier_protein_E2 <=> glycine_cleavage_system_H + enzyme_N6-(dihydrolipoyl)lysine
|
not assigned
|
–
|
K
|
| |
KEGG:
R12432
|
|
|
|
enzyme_N6-(dihydrolipoyl)lysine + ROOH <=> Enzyme_N6-(lipoyl)lysine + H2O + rhodopsin
|
1.11.1.28
lipoyl-dependent peroxiredoxin
|
–
|
|
| |
KEGG:
R12603
|
|
|
|
enzyme_N6-(dihydrolipoyl)lysine + [2-Cys_peroxiredoxin]_with_a_disulfide_bond <=> [dihydrolipoyllysine-residue(2-methylpropanoyl)transferase]-lipoyllysine + [2-Cys_peroxiredoxin]_with_reduced_L-cysteine_residues
|
not assigned
|
–
|
|
| |
MetaCyc:
RXN-20689
|
|
|
|
succinyl-CoA + enzyme_N6-(dihydrolipoyl)lysine <=> CoA + [2-oxoglutarate_dehydrogenase_E2_protein]_N6-S-succinyldihydrolipoyl-L-lysine
|
2.3.1.61
dihydrolipoyllysine-residue succinyltransferase
|
–
|
M
|
| |
MetaCyc:
RXN0-1147
|
|
|
|
S-adenosyl-L-methionine + a_[lipoyl-carrier_protein]-N6-octanoyl-L-lysine + [Fe-S]_cluster_scaffold_protein_carrying_a_[4Fe-4S]+2_cluster + H+ + reduced_ferredoxin_[iron-sulfur]_cluster <=> enzyme_N6-(dihydrolipoyl)lysine + 5''-deoxyadenosine + L-methionine + an_[Fe-S]_cluster_scaffold_protein + S2- + Fe2+ + oxidized_ferredoxin
|
2.8.1.8
lipoyl synthase
|
–
|
M
|
| |
MetaCyc:
RXN0-949
|
|
|
|
S-aminomethyldihydrolipoylprotein + tetrahydrofolate <=> enzyme_N6-(dihydrolipoyl)lysine + 5,10-methylenetetrahydrofolate + NH3
|
2.1.2.10
aminomethyltransferase
|
–
|
|
| |
BRENDA:
BR43939
|
|
|
|
protein_N6-(octanoyl)lysine + an_[Fe-S]_cluster_scaffold_protein_carrying_a_[4Fe-4S]2+_cluster + 2 S-adenosyl-L-methionine + 2 [2Fe-2S]-center + 6 H+ <=> enzyme_N6-(dihydrolipoyl)lysine + an_[Fe-S]_cluster_scaffold_protein + 2 Sulfide + 4 Fe3+ + 2 L-methionine + 2 5''-deoxyadenosine + 2 [2Fe-2S]-center
|
2.8.1.8
lipoyl synthase
|
–
|
|
| |
BRENDA:
BR48680
|
|
